人类

IL5RA - Interleukin 5 Receptor Subunit Alpha

Alias:
IL5R
CD125
CDw125
HSIL5R3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种异源二聚细胞因子受体的白细胞介素5特异性亚单位。该受体由配体特异性的α亚单位和信号传导β亚单位组成,这些亚单位由白细胞介素3(IL3)、集落刺激因子2(CSF2/GM-CSF)和白细胞介素5(IL5)的受体共享。这个蛋白质与IL5的结合依赖于β亚单位。β亚单位被配体激活,并是IL5生物活性的必需成分。已发现这个蛋白质与合成素(syntenin)相互作用,合成素是IL5介导的转录因子SOX4激活所必需的。已经报道了几种可变剪接的转录变异体,编码四种不同的异构体。[由RefSeq,2011年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
12
44051 bp
47.69
22
--
4
11

IL5RA Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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