人类

IL5 - Interleukin 5

Alias:
EDF
TRF
IL-5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种细胞因子,作为B细胞和嗜酸性粒细胞的生长和分化因子。编码的细胞因子在嗜酸性粒细胞形成、成熟、募集和存活的调节中扮演主要角色。这种细胞因子的产生增加可能与嗜酸性粒细胞依赖的炎症疾病的病理生理有关。这种细胞因子通过与其作为异源二聚体的受体结合来发挥作用,其β亚单位与白细胞介素3(IL3)和集落刺激因子2(CSF2/GM-CSF)的受体共享。这个基因位于染色体5上的一个细胞因子基因簇中,该基因簇包括白细胞介素4(IL4)、白细胞介素13(IL13)和CSF2。这个基因、IL4和IL13可能受到染色体5q31上120千碱基对上的长程调节元件的协调调控。[RefSeq,2013年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
4
15371 bp
15.24
6
--
8
14

IL5 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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