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中文人类
IL3RA - Interleukin 3 Receptor Subunit Alpha
Alias:
IL3R
CD123
IL3RX
IL3RY
IL3RAY
hIL-3Ra
IL-3R-alpha
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这个基因编码的蛋白质是一种异源二聚体细胞因子受体的白介素3特异性亚单位。受体由配体特异性的α亚单位和信号传导β亚单位组成，这些亚单位由白介素3（IL3）、集落刺激因子2（CSF2/GM-CSF）和白细胞介素5（IL5）受体共享。这个蛋白质与IL3的结合依赖于β亚单位。β亚单位被配体激活，并是IL3生物活性的必需成分。这个基因和编码集落刺激因子2受体α链（CSF2RA）的基因在染色体X或Y的X-Y伪常染色体区域形成一个细胞因子受体基因簇。已经发现了编码不同异型体的替代剪接转录变异体。[由RefSeq，2012年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IL3RA Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
