Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
IL2RB - Interleukin 2 Receptor Subunit Beta
Alias:
CD122
IMD63
IL15RB
P70-75
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
白细胞介素2受体,参与T细胞介导的免疫反应,以3种形式存在,分别具有结合白细胞介素2的能力。低亲和力形式是α亚基的单体,不参与信号传导。中等亲和力形式由α/β亚基异二聚体组成,而高亲和力形式由α/β/γ亚基异三聚体组成。受体的中等和高亲和力形式参与受体介导的内吞作用和白细胞介素2的有丝分裂信号的传导。这个基因编码的蛋白质代表β亚基,是一类I型膜蛋白。使用替代启动子导致编码相同蛋白质的多种转录变异体。蛋白质主要在造血系统中表达。一些变异体在上游长终端重复(LTR)中使用替代启动子,导致胎盘特异性的表达。[RefSeq,2016年9月提供]
Related ID:
NCBI:3560
ENSEMBL:ENSG00000100385
HGNC:6009
UNIPROT:P14784
OMIM:146710
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3560
3
10
49281 bp
61.12
293
4
8
13
IL2RB Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top