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中文人类
FASLG - Fas Ligand
Alias:
APTL
FASL
CD178
CD95L
ALPS1B
CD95-L
TNFSF6
TNLG1A
APT1LG1
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这个基因是肿瘤坏死因子超家族的成员。编码的跨膜蛋白的主要功能是通过与FAS结合触发细胞凋亡。FAS/FASLG信号通路对免疫系统的调节至关重要，包括T细胞的激活诱导细胞死亡（AICD）和细胞毒性T淋巴细胞诱导的细胞死亡。它还与几种癌症的发展有关。这个基因的缺陷可能与某些系统性红斑狼疮（SLE）病例有关。已经描述了可变剪接的转录变异体。[RefSeq,2014年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FASLG Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
