人类

IL2 - Interleukin 2

Alias:
IL-2
TCGF
lymphokine
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是白细胞介素2(IL2)细胞因子亚家族的成员,包括IL4、IL7、IL9、IL15、IL21、红细胞生成素和血小板生成素。这个基因编码的蛋白质是一种由激活的CD4+和CD8+T淋巴细胞产生的分泌型细胞因子,对T和B淋巴细胞的增殖非常重要。这个细胞因子的受体(IL2R)是一种异源三聚体蛋白质复合物,其γ链也由IL4和IL7共享。这个基因在成熟胸腺细胞中的表达是单等位基因的,这代表了一种罕见的调控模式,用于精确控制单个基因的表达。在小鼠中类似基因的靶向破坏导致溃疡性结肠炎样疾病,这表明这个基因在抗原刺激免疫反应中具有基本作用。[RefSeq,2020年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
4
5256 bp
17.63
2
--
12
25

IL2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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