人类

IL1RN - Interleukin 1 Receptor Antagonist

Alias:
DIRA
IRAP
IL1F3
IL1RA
MVCD4
IL-1RN
IL-1ra
IL-1ra3
ICIL-1RA
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白细胞介素1细胞因子家族的一员。这个蛋白质抑制白细胞介素1α(IL1A)和白细泡介素1β(IL1B)的活性,并调节各种与白细胞介素1相关的免疫和炎症反应,特别是在感染和炎症的急性阶段。这个基因和另外五个密切相关的细胞因子基因在染色体2上形成一个大约跨越400kb的基因簇。这个基因的一个多态性与骨质疏松性骨折和胃癌的风险增加有关。已经报道了几种编码不同异型体的可变剪接转录本变异体。[由RefSeq,2020年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10
4
34655 bp
20.05
198
3
8
26

IL1RN Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top