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中文人类
IGLL1 - Immunoglobulin Lambda Like Polypeptide 1
Alias:
IGO
14.1
AGM2
IGL1
IGL5
IGLL
IGVPB
CD179b
VPREB2
IGLJ14.1
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前B细胞受体存在于proB和preB细胞的表面，参与细胞增殖、从proB细胞向preB细胞阶段的分化、Ig重链基因座的等位基因排除以及Ig轻链基因重排的信号传导。前B细胞受体由与异源二聚体替代轻链结合的膜结合Ig mu重链组成。该基因编码替代轻链亚基之一，是免疫球蛋白基因超家族的成员。该基因不经历重排。该基因的突变可能导致B细胞缺陷和无丙种球蛋白症，这是一种少或无γ球蛋白或抗体的常染色体隐性疾病。已发现该基因有两个编码不同异构体的转录变异体。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IGLL1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
