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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
KLK3 - Kallikrein Related Peptidase 3
Alias:
APS
PSA
hK3
KLK2A1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
血清酸性磷酸酶-1是一种位于染色体19上的15个血清酸性磷酸酶亚家族成员之一。它编码一种单链糖蛋白,这是一种在前列腺腺管上皮细胞中合成并在精液血浆中存在的蛋白酶。据认为,它正常地参与精液凝块的液化,可能是通过水解高分子质量的精液囊蛋白。在临床环境中,这种蛋白质被称为PSA,其血清水平在前列腺癌的诊断和监测中有用。这种基因的可变剪接产生了几个转录变异体,编码不同的异构体。[RefSeq,2019年12月提供]
Related ID:
NCBI:354
ENSEMBL:ENSG00000142515
HGNC:6364
UNIPROT:P07288
OMIM:176820
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
354
3
5
5850 bp
28.74
26
--
5
22
KLK3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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