Cyp11b3 - cytochrome P450, family 11, subfamily b, polypeptide 3

Enables corticosterone 18-monooxygenase activity and steroid 11-beta-monooxygenase activity. Involved in adrenal gland development; response to peptide hormone; and steroid metabolic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in corticosterone methyloxidase deficiency 1; diabetes mellitus (multiple); dilated cardiomyopathy 1H; hypertension (multiple); and primary hyperaldosteronism. Orthologous to human CYP11B2 (cytochrome P450 family 11 subfamily B member 2). [provided by Alliance of Genome Resources, Apr 2022]