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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Gsdme - gasdermin E
Alias:
Dfna5
Dfna5h
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活卡介脂素结合活性;磷酸肌醇-4,5-二磷酸酯结合活性;以及宽孔通道活性。参与多个过程,包括细胞对肿瘤坏死因子的反应;颗粒酶介导的程序性细胞死亡信号通路;以及细胞内信号传导的正调控。预测在耳内感受器细胞分化的上游或内部发挥作用。预测位于细胞质和质膜上。该基因的人类同源物与常染色体显性非综合征性耳聋5和感音神经性听力损失有关。与人类的GSDME(气囊肿素E)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:353316
ENSEMBL:ENSRNOG00000009970
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
353316
8
10
62331 bp
Unknown
12
1
Gsdme Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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References Literature
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IF
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