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中文人类
IGFBP7 - Insulin Like Growth Factor Binding Protein 7
Alias:
AGM
PSF
TAF
FSTL2
IBP-7
MAC25
IGFBP-7
RAMSVPS
IGFBP-7v
IGFBPRP1
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这个基因编码胰岛素样生长因子(IGF)结合蛋白(IGFBP)家族的成员。IGFBPs以高亲和力结合IGFs，并调节体液和组织中IGF的可用性，以及调节其与受体的结合。这个蛋白以相对较低的亲和力结合IGF-I和IGF-II，属于低亲和力IGFBP亚家族。它还可以刺激前列腺环素产生和细胞粘附。这个基因的不同剪接转录变异体已经描述，编码不同的异构体，其中一个变异体与视网膜动脉大动脉瘤有关(PMID:21835307)。[由RefSeq提供，2011年12月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IGFBP7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
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Related Mouse Models
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MGI
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Link
References Literature
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