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中文人类
IGF2R - Insulin Like Growth Factor 2 Receptor
Alias:
MPR1
MPRI
CD222
CIMPR
M6P-R
MPR300
CI-M6PR
MPR 300
M6P/IGF2R
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这个基因编码一个同时结合胰岛素样生长因子2和甘露糖6-磷酸的受体。每个配体的结合位点位于蛋白质的不同区域。这个受体具有多种功能，包括在溶酶体酶的细胞内转运、转化生长因子β的激活以及胰岛素样生长因子2的降解。这个基因的突变或杂合性缺失与肝细胞癌的风险增加有关。小鼠的同源基因是印迹的，并且只从母源等位基因进行表达；然而，人类基因的印迹可能是多态性的，因为只有少数个体表现出母源等位基因的偏斜表达（PMID:8267611）。[由RefSeq，2015年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IGF2R Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
