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中文人类
IGF1R - Insulin Like Growth Factor 1 Receptor
Alias:
IGFR
CD221
IGFIR
JTK13
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这个受体以高亲和力结合胰岛素样生长因子，具有酪氨酸激酶活性。胰岛素样生长因子I受体在转化事件中起着关键作用。前体切割产生α和β亚基。在大多数恶性组织中，其表达过度，通过增强细胞存活作用，作为抗凋亡剂发挥作用。已发现这个基因的替代剪接转录变异体编码不同的异构体。[RefSeq,2014年5月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IGF1R Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
