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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MACC1 - MET Transcriptional Regulator MACC1
Alias:
7A5
SH3BP4L
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
MACC1是肝细胞生长因子(HGF;MIM 142409)-HGF受体(HGFR或MET;MIM 164860)途径的关键调节因子,该途径涉及细胞生长、上皮-间质转化、血管生成、细胞迁移、侵袭和转移。结肠癌(MIM 114500)标本中MACC1的表达是转移形成和无转移生存期的独立预后指标(Stein等人,2009年[PubMed 19098908])。[由OMIM于2009年3月提供]
Related ID:
NCBI:346389
ENSEMBL:ENSG00000183742
HGNC:30215
UNIPROT:Q6ZN28
OMIM:612646
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
346389
1
7
82730 bp
96.64
37
--
3
7
MACC1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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