人类

IFNB1 - Interferon Beta 1

Alias:
IFB
IFF
IFNB
IFN-beta
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种属于干扰素家族的信号蛋白的细胞因子,作为天生免疫反应的一部分,对病原体产生反应。这个基因编码的蛋白质属于I型干扰素,对于抵抗病毒感染非常重要。此外,I型干扰素参与细胞分化和抗肿瘤防御。在受到病原体刺激后,I型干扰素与同源受体复合物结合,并诱导编码炎性细胞因子和趋化因子的基因的转录。I型干扰素分泌的过度激活与自身免疫性疾病有关。缺乏这个基因的小鼠表现出几种表型,包括B细胞成熟缺陷和对病毒感染的易感性增加。[RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
1
839 bp
22.29
13
--
11
24

IFNB1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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