人类

IFNA2 - Interferon Alpha 2

Alias:
IFNA
IFNA2B
leIF A
IFN-alphaA
IFN-alpha-2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是染色体9上α干扰素基因簇的成员。编码的细胞因子是I型干扰素家族的一员,在病毒感染后产生,作为先天免疫反应的关键部分,具有强大的抗病毒、抗增殖和免疫调节特性。这种细胞因子与其他I型干扰素一样,结合由IFNAR1和IFNAR2组成的普遍表达的血浆膜受体,因此能够作用于几乎所有身体细胞。编码的蛋白质能有效减轻普通感冒的症状和持续时间,并治疗许多类型的癌症,包括某些血液恶性肿瘤和实体瘤。认为血液中I型干扰素的缺乏是严重COVID-19的标志性特征,可能为联合治疗方法提供理论依据。[RefSeq,2020年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
1
1144 bp
21.58
15
--
17
21

IFNA2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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