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中文人类
STING1 - Stimulator Of Interferon Response CGAMP Interactor 1
Alias:
ERIS
MITA
MPYS
SAVI
NET23
STING
hMITA
hSTING
TMEM173
STING-beta
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这个基因编码一个五跨膜蛋白，作为对病毒和细菌感染的自然免疫反应的主要调节因子。编码的蛋白质是一种模式识别受体，可以检测胞浆核酸并传递激活I型干扰素反应的信号。该蛋白质还被证明通过与II型主要组织相容性复合体结合，在凋亡信号传导中发挥作用。这个基因的突变是导致婴儿起病的STING相关血管病变的原因。交替剪接导致多个转录变异体。[RefSeq,2014年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
STING1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
