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中文人类
IRF8 - Interferon Regulatory Factor 8
Alias:
ICSBP
IRF-8
ICSBP1
IMD32A
IMD32B
H-ICSBP
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干扰素共有序列结合蛋白（ICSBP）是干扰素（IFN）调节因子（IRF）家族的转录因子。这个家族的蛋白质由保守的N-端区域的DNA结合域和作为调节域的分歧C-端区域组成。IRF家族蛋白质结合到IFN刺激响应元素（ISRE）并调节I型IFNs，即IFN-alpha和IFN-beta刺激的基因的表达。IRF家族蛋白质还控制由病毒感染诱导的IFN-alpha和IFN-beta调节的基因的表达。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IRF8 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
