人类

CLEC4G - C-type Lectin Domain Family 4 Member G

Alias:
LP2698
UNQ431
DTTR431
LSECtin
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个糖结合受体,属于C型凝集素家族,在免疫应答中发挥作用。C型凝集素受体是位于免疫细胞上的模式识别受体,负责识别和摄取自身和非自身的糖蛋白,并调节细胞粘附、糖蛋白清除和细胞信号传导功能。这个基因的蛋白质结合埃博拉病毒、西尼罗病毒和SARS冠状病毒的病毒包膜蛋白的复杂型N-糖,但不结合HIV或丙型肝炎病毒。在鼠中,这个蛋白质被证明能识别活化的T细胞,并负调节T细胞受体介导的信号传导。它还可以作为小鼠中NK细胞介导免疫的新的、肝脏特异性的调节因子。已经发现这个基因的不同转录变异体编码不同的异构体。[RefSeq,2020年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
9
3154 bp
32.56
5
--
6
8

CLEC4G Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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