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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CLEC4G - C-type Lectin Domain Family 4 Member G
Alias:
LP2698
UNQ431
DTTR431
LSECtin
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个糖结合受体,属于C型凝集素家族,在免疫应答中发挥作用。C型凝集素受体是位于免疫细胞上的模式识别受体,负责识别和摄取自身和非自身的糖蛋白,并调节细胞粘附、糖蛋白清除和细胞信号传导功能。这个基因的蛋白质结合埃博拉病毒、西尼罗病毒和SARS冠状病毒的病毒包膜蛋白的复杂型N-糖,但不结合HIV或丙型肝炎病毒。在鼠中,这个蛋白质被证明能识别活化的T细胞,并负调节T细胞受体介导的信号传导。它还可以作为小鼠中NK细胞介导免疫的新的、肝脏特异性的调节因子。已经发现这个基因的不同转录变异体编码不同的异构体。[RefSeq,2020年4月提供]
Related ID:
NCBI:339390
ENSEMBL:ENSG00000182566
HGNC:24591
UNIPROT:Q6UXB4
OMIM:616256
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Reference
339390
2
9
3154 bp
32.56
5
--
6
8
CLEC4G Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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