人类

ICAM3 - Intercellular Adhesion Molecule 3

Alias:
CD50
CDW50
ICAM-R
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是细胞间粘附分子(ICAM)家族的一员。所有ICAM蛋白质都是类型I跨膜糖蛋白,包含2-9个免疫球蛋白样C2型结构域,并与白细胞粘附分子LFA-1蛋白质结合。这个蛋白质在所有白细胞中组成性和大量表达,可能是免疫反应启动中LFA-1最重要的配体。它不仅作为粘附分子发挥作用,还作为强大的信号分子发挥作用。可变剪接导致多个转录变异体,编码不同的异构体。[RefSeq,2016年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
7
5849 bp
59.54
26
--
--
15

ICAM3 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top