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中文人类
IARS1 - Isoleucyl-tRNA Synthetase 1
Alias:
IRS
IARS
ILRS
ILERS
GRIDHH
PRO0785
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氨基酸-tRNA合成酶通过其相应的氨基酸催化tRNA的氨基酸化。由于其在将氨基酸与tRNA中的核苷酸三联体连接起来的核心作用，氨基酸-tRNA合成酶被认为是进化中最早出现的蛋白质之一。异亮氨酸-tRNA合成酶属于I类氨基酸-tRNA合成酶家族，已被鉴定为自身免疫性疾病多发性肌炎/皮肌炎的自身抗体靶点。已经发现了可变剪接的转录变异体。[RefSeq, Nov 2012提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IARS1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
