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中文人类
HTR2A - 5-hydroxytryptamine Receptor 2A
Alias:
HTR2
5-HT2A
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这个基因编码一种血清素的受体，血清素是一种具有多种功能的神经递质。这个基因的突变与精神分裂症和强迫症易感性有关，也与抑郁症患者对抗抑郁药西酞普兰的反应有关。在2号内含子有突变的抑郁症患者对西酞普兰的反应显著降低，因为这种抗抑郁药降低了该基因的表达。已经发现这个基因有多种编码不同异构体的转录变异体。[RefSeq，2009年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HTR2A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
