Cngb1 - cyclic nucleotide gated channel beta 1

Enables cyclic nucleotide-gated ion channel activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of smell; ion channel modulating, G protein-coupled receptor signaling pathway; and response to odorant. Acts upstream of or within several processes, including photoreceptor cell maintenance; photoreceptor cell outer segment organization; and sensory perception of smell. Located in membrane and photoreceptor outer segment. Is expressed in several structures, including head mesenchyme; incisor; limb; sensory organ; and skeleton. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 45. Orthologous to human CNGB1 (cyclic nucleotide gated channel subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]