人类

DNAJA1 - DnaJ Heat Shock Protein Family (Hsp40) Member A1

Alias:
DJ-2
DjA1
HDJ2
HSDJ
HSJ2
HSJ-2
HSPF4
NEDD7
hDJ-2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码DnaJ家族蛋白质的一员,作为热激蛋白70的辅助伴侣。热激蛋白促进蛋白质折叠、运输、防止聚集和蛋白水解降解。这个家族的成员的特征是一个高度保守的N-末端J结构域、一个富含甘氨酸/苯丙氨酸的区域、四个CxxCxGxG锌指重复序列和一个C-末端底物结合结构域。J结构域调节与热激蛋白70的相互作用,以招募底物并调节ATP水解活性。在人类中,这个基因已被证明通过被流感病毒A的共选用途参与正调控病毒复制。在其他染色体上发现了这个基因的几个假基因。[RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
9
14635 bp
44.87
6
--
5
25

DNAJA1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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