人类

BIRC3 - Baculoviral IAP Repeat Containing 3

Alias:
AIP1
API2
MIHC
CIAP2
HAIP1
HIAP1
IAP-1
MALT2
RNF49
c-IAP2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码IAP家族的一员,通过结合肿瘤坏死因子受体相关因子TRAF1和TRAF2来抑制细胞凋亡,可能通过干扰ICE样蛋白酶的激活。编码的蛋白质可抑制血清缺乏引起的细胞凋亡,但对由暴露于强自由基诱导剂甲萘醌引起的细胞凋亡没有影响。它包含3个杆状病毒IAP重复序列和一个环指结构域。已经发现了编码相同异型的转录变异体。[RefSeq,2011年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
9
21920 bp
68.37
25
1
9
15

BIRC3 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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