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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ep300 - E1A binding protein p300
Alias:
p300
KAT3B
p300 HAT
A430090G16
A730011L11
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括N-酰基转移酶活性;核酸结合活性;和p53结合活性。参与多个过程,包括面部形态发生;参与未折叠蛋白应答的RNA聚合酶II启动子的正向调控;和蛋白质酰化。在几个过程的上游或内部发挥作用,包括动物器官发育;组蛋白H3-K56乙酰化;和基因表达调控。组蛋白乙酰转移酶复合物和转录调节物复合物的一部分。在几个结构中表达,包括消化系统;心脏;肺;神经系统;和皮肤。用于研究系统性红斑狼疮。这个基因的人类同源物涉及Rubinstein-Taybi综合征;结直肠癌;和充血性心力衰竭。与人EP300(E1A结合蛋白p300)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:328572
ENSEMBL:ENSMUSG00000055024
UNIPROT:B2RWS6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
328572
5
31
65950 bp
263.31
14
28
Ep300 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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