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中文小鼠
Dna2 - DNA replication helicase/nuclease 2
Alias:
Dna2l
E130315B21Rik
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具有5'-flap endonuclease活性。参与有丝分裂期端粒维持，通过半保守复制和核酸磷酸二酯键水解。位于染色体端粒区。该基因的人类同源物与Seckel综合征8、常染色体显性进行性外眼肌麻痹伴线粒体DNA缺失6、孤立的生长激素缺乏类型IA和线粒体肌病有关。与人类的DNA2（DNA复制解旋酶/核酸酶2）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Dna2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
