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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PRMT1 - Protein Arginine Methyltransferase 1
Alias:
ANM1
HCP1
IR1B4
HRMT1L2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码蛋白质精氨酸N-甲基转移酶(PRMT)家族的成员。PRMTs对靶蛋白的翻译后修饰在许多生物过程中起着重要的调控作用,其中PRMT通过将S-腺苷-L-甲硫氨酸的甲基基团转移到胍的末端氮原子上来甲基化精氨酸残基。编码的蛋白质是I型PRMT,负责细胞中大部分精氨酸甲基化活性。这个基因的过表达可能在许多类型的癌症中发挥作用。已经观察到这个基因的替代剪接转录变异体编码多种异构体,这个基因的假基因位于染色体5的长臂上。[RefSeq,2011年12月提供]
Related ID:
NCBI:3276
ENSEMBL:ENSG00000126457
HGNC:5187
UNIPROT:Q99873
OMIM:602950
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3276
7
11
12295 bp
42.46
13
--
9
31
PRMT1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Type
Name
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CAS Number
Status
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Link
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References Literature
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