人类

PRMT1 - Protein Arginine Methyltransferase 1

Alias:
ANM1
HCP1
IR1B4
HRMT1L2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码蛋白质精氨酸N-甲基转移酶(PRMT)家族的成员。PRMTs对靶蛋白的翻译后修饰在许多生物过程中起着重要的调控作用,其中PRMT通过将S-腺苷-L-甲硫氨酸的甲基基团转移到胍的末端氮原子上来甲基化精氨酸残基。编码的蛋白质是I型PRMT,负责细胞中大部分精氨酸甲基化活性。这个基因的过表达可能在许多类型的癌症中发挥作用。已经观察到这个基因的替代剪接转录变异体编码多种异构体,这个基因的假基因位于染色体5的长臂上。[RefSeq,2011年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
11
12295 bp
42.46
13
--
9
31

PRMT1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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