Log In|Sign Up
中文人类
APEH - Acylaminoacyl-peptide Hydrolase
Alias:
APH
OPH
AARE
ACPH
D3S48E
D3F15S2
DNF15S2
Favorite
这个基因编码酰肽水解酶，该酶优先水解小型乙酰化肽中的末端乙酰化氨基酸。通过这个水解酶形成的乙酰氨基酸进一步被氨基酰基酶加工成乙酸和自由氨基酸。这个基因位于染色体3号染色体区段（3p21）与氨基酰基酶基因相同的位置，该位置的缺失也与氨基酰基酶活性降低有关。酰肽水解酶是一种300kDa的同源四聚体蛋白，每个亚单位由732个氨基酸残基组成。它可以在活细胞中破坏氧化损伤的蛋白质中发挥重要作用。这个基因座缺失在各种类型的癌（如小细胞肺癌和肾细胞癌）中都有发现。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
APEH Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
