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中文人类
HOXB8 - Homeobox B8
Alias:
HOX2
HOX2D
Hox-2.4
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这个基因是Antp homeobox家族的成员，编码具有homeobox DNA结合结构的核蛋白。它被包含在位于染色体17上的homeobox B基因簇中。编码的蛋白质作为参与发育的序列特异性转录因子发挥作用。这个基因的表达增加与结直肠癌有关。已经敲除了这个基因的鼠正链分子的小鼠表现出过度病理性的梳理行为。这个行为与患有强迫症谱系障碍拔毛狂的人的行为相似。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HOXB8 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
