Apba1 - amyloid beta (A4) precursor protein binding, family A, member 1

Predicted to enable PDZ domain binding activity; amyloid-beta binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including amino acid transport; in utero embryonic development; and intracellular protein transport. Located in glutamatergic synapse and presynaptic active zone membrane. Is active in Schaffer collateral - CA1 synapse. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human APBA1 (amyloid beta precursor protein binding family A member 1). [provided by Alliance of Genome Resources, Apr 2022]