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中文小鼠
Lig4 - ligase IV, DNA, ATP-dependent
Alias:
tiny
5830471N16Rik
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具有ATP结合活性和DNA连接酶(ATP)活性。参与非同源末端连接的双链断裂修复。在几个过程的上游或内部发挥作用，包括DNA代谢过程、造血和神经系统发育。是DNA依赖的蛋白激酶-DNA连接酶4复合物的一部分。在肾单位中表达。用于研究DNA连接酶IV缺陷。该基因的人类同源物涉及几种疾病，包括DNA连接酶IV缺陷、结直肠癌、高级别脑胶质瘤、多发性骨髓瘤和前列腺癌。与人类LIG4(DNA连接酶4)正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Lig4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
