Ocrl - OCRL, inositol polyphosphate-5-phosphatase

Predicted to enable GTPase activator activity; phosphatase activity; and small GTPase binding activity. Predicted to be involved in cilium assembly; dephosphorylation; and regulation of GTPase activity. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in several cellular components, including cytoplasmic vesicle; photoreceptor outer segment; and trans-Golgi network. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in Dent disease and oculocerebrorenal syndrome. Orthologous to human OCRL (OCRL inositol polyphosphate-5-phosphatase). [provided by Alliance of Genome Resources, Apr 2022]