Tlr7 - toll-like receptor 7

Predicted to enable RNA binding activity and pattern recognition receptor activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of cytokine production; and response to virus. Predicted to act upstream of or within regulation of protein phosphorylation. Predicted to be located in cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in COVID-19 and X-Linked immunodeficiency 74. Orthologous to human TLR7 (toll like receptor 7). [provided by Alliance of Genome Resources, Apr 2022]