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中文大鼠
Mdm2 - MDM2 proto-oncogene
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激活p53结合活性；信号受体结合活性；和泛素蛋白连接酶活性。参与几个过程，包括细胞对激素刺激的响应；蛋白水解的负调控；和生物碱响应。位于几个细胞成分中，包括胞质；核；和突触。用于研究鱼鳞病；创伤后应激障碍；和短暂脑缺血。乳腺癌；间歇性跛行；肝病；胰腺炎；和阴茎异常勃起的生物标志物。这个基因的人类同源物涉及慢性髓性白血病；成胶质细胞瘤；肝细胞癌；胰腺癌；和肉瘤。正交人类MDM2(MDM2原癌基因)。[由基因组资源联盟，2022年4月提供]
Related ID：
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Mdm2 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
