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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
HMGB2 - High Mobility Group Box 2
Alias:
HMG2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个非组蛋白染色体高移动性组蛋白家族成员。这个家族的蛋白质与染色质相关,并在高等真核细胞核中普遍分布。体外研究表明,这种蛋白质能够高效地弯曲DNA并形成DNA圈。这些研究表明,通过促进DNA的灵活性,在顺式作用蛋白质之间的协同相互作用中发挥作用。该蛋白质还被报道参与DNA末端连接过程中的DNA双链断裂修复和V(D)J重组的最终连接步骤。[由RefSeq,2008年7月提供]
Related ID:
NCBI:3148
ENSEMBL:ENSG00000164104
HGNC:5000
UNIPROT:P26583
OMIM:163906
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3148
3
5
2983 bp
24.03
4
--
5
21
HMGB2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Related Mouse Models
Type
Name
MGI
Strain of Origin
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Mutations
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Status
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Link
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References Literature
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IF
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