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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
HMGB1 - High Mobility Group Box 1
Alias:
HMG1
HMG3
HMG-1
SBP-1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个属于高流动性组盒超家族的蛋白质。该编码的非组蛋白核DNA结合蛋白调节转录,并参与DNA的组织。该蛋白质在包括炎症、细胞分化和肿瘤细胞迁移在内的几个细胞过程中发挥作用。已经发现了这个基因的多个假基因。替代剪接产生了多个编码相同蛋白质的转录变异体。[RefSeq,2015年9月提供]
Related ID:
NCBI:3146
ENSEMBL:ENSG00000189403
HGNC:4983
UNIPROT:P09429
OMIM:163905
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3146
10
5
160894 bp
24.89
14
1
10
74
HMGB1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Score
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No data available
Transcripts & Proteins
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
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Status
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References Literature
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