Sptb - spectrin, beta, erythrocytic

Predicted to enable actin filament binding activity and ankyrin binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within hemopoiesis; plasma membrane organization; and porphyrin-containing compound biosynthetic process. Predicted to be located in several cellular components, including cell surface; cytoskeleton; and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 2. Orthologous to human SPTB (spectrin beta, erythrocytic). [provided by Alliance of Genome Resources, Apr 2022]