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Ago1 - argonaute RISC component 1

Alias:
Eif2c1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码argonaute家族的一员,该家族与小型RNA结合并在RNA干扰(RNAi)和RNA沉默中扮演重要角色。这种蛋白质结合microRNAs(miRNAs)或小干扰RNAs(siRNAs),并抑制与其互补的mRNA的翻译。它还在与结合的短反义基因RNA(agRNAs)互补的启动子区域中的转录基因沉默(TGS)中发挥作用,以及在与miRNA结合的mRNA靶标中的降解。最近的研究表明,这个基因是一个真正的终止密码子穿透靶标,其mRNA可以通过使用可选的帧内翻译终止密码子产生一个C端延伸的异构体。[由RefSeq,2015年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
6
19
35008 bp
Unknown
10
1

Ago1 Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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