Eps15 - epidermal growth factor receptor pathway substrate 15

Predicted to enable identical protein binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including endocytic recycling; positive regulation of receptor recycling; and postsynaptic neurotransmitter receptor internalization. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and early endosome. Is active in glutamatergic synapse. Orthologous to human EPS15 (epidermal growth factor receptor pathway substrate 15). [provided by Alliance of Genome Resources, Apr 2022]