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中文人类
HLA-DRB5 - Major Histocompatibility Complex, Class II, DR Beta 5
Alias:
DRB5
HLA-DRB5*
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HLA-DRB5属于HLA II类β链平行系。这个II类分子是一个由α（DRA）和β（DRB）链组成的异源二聚体，两者都锚定在膜上。它通过呈现来自细胞外蛋白的肽发挥作用，在免疫系统中扮演重要角色。II类分子在抗原呈递细胞中表达。β链约为26-28 kDa，其基因包含6个外显子。外显子1编码前导肽，外显子2和3编码两个细胞外结构域，外显子4编码跨膜结构域，外显子5编码胞质尾。在DR分子中，β链包含指定肽结合特异性的所有多态性。对于骨髓和肾脏移植，这些多态性的分型是常规的。该基因有多个假基因。[RefSeq，2020年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HLA-DRB5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
