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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Fancd2 - FA complementation group D2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有预测的DNA聚合酶结合活性。参与几个过程,包括链间交叉连接修复;减数分裂I;和有丝分裂内S期DNA损伤检查点信号传导。在几个过程的上游或内部发挥作用,包括神经元干细胞群维护;CD40信号通路调控;和调节性T细胞分化的调控。位于细胞质;核团;和核仁中。在浓缩的染色体和细胞核中活跃。该基因的人类同源物涉及范科尼贫血;范科尼贫血互补组D2;和乳腺癌。与人类FANCD2(FA互补组D2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:312641
ENSEMBL:ENSRNOG00000061085
UNIPROT:Q6IV68
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
312641
4
44
64409 bp
163.62
8
2
Fancd2 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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