Abl1 - ABL proto-oncogene 1, non-receptor tyrosine kinase

Enables delta-catenin binding activity; protein kinase activity; and protein kinase binding activity. Involved in several processes, including glomerular visceral epithelial cell apoptotic process; positive regulation of cellular component organization; and positive regulation of programmed cell death. Located in several cellular components, including growth cone; neuronal cell body; and ruffle. Biomarker of Parkinson's disease and ureteral obstruction. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); leukemia (multiple); and lung non-small cell carcinoma. Orthologous to human ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]