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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Itch - itchy E3 ubiquitin protein ligase
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测具有多种功能,包括arrestin家族蛋白结合活性;泛素蛋白连接酶活性;以及泛素样蛋白连接酶结合活性。参与多个过程,包括负调控JNK级联反应;负调控NF-kappaB转录因子活性;以及蛋白质泛素化。在多个过程的上游或内部发挥作用,包括细胞蛋白质代谢过程;负调控α-β T细胞增殖;以及T细胞疲劳的正调控。位于多个细胞组件中,包括细胞皮质;胞质囊泡;以及核质。是含有蛋白质的复合物的一部分。与早期内体共定位。正交人类ITCH(痒E3泛素蛋白连接酶)。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:311567
ENSEMBL:ENSRNOG00000059043
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
311567
2
25
91398 bp
Unknown
7
3
Itch Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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No Data Found!
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