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中文人类
HLA-DPA1 - Major Histocompatibility Complex, Class II, DP Alpha 1
Alias:
DPA1
PLT1
HLADP
HLASB
DP(W3)
DP(W4)
HLA-DPA
HLA-DP1A
HLA-DPB1
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HLA-DPA1属于HLA II类α链平行系。这个II类分子是一个由α(DPA)和β(DPB)链组成的异二聚体，两者都固定在膜上。它通过呈现来自细胞外蛋白的肽发挥作用，在免疫系统中扮演重要角色。II类分子在抗原呈递细胞（APC：B淋巴细胞，树突状细胞，巨噬细胞）中表达。α链约为33-35 kDa，其基因包含5个外显子。外显子1编码前导肽，外显子2和3编码两个细胞外结构域，外显子4编码跨膜结构域和胞质尾。在DP分子中，α链和β链都含有指定肽结合特异性的多态性，从而产生多达4种不同的分子。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HLA-DPA1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
