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中文人类
HLA-DOB - Major Histocompatibility Complex, Class II, DO Beta
Alias:
DOB
HLA_DOB
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HLA-DOB属于HLA II类β链平行系。这个II类分子是一个由α(DOA)和β链(DOB)组成的核心异二聚体，两者都固定在膜上。它位于细胞内囊泡中。DO通过抑制HLA-DM来抑制MHC II类分子的肽加载。II类分子在抗原呈递细胞（APC：B淋巴细胞，树突状细胞，巨噬细胞）中表达。β链约26-28 kDa，其基因包含6个外显子。外显子1编码前导肽，外显子2和3编码两个细胞外结构域，外显子4编码跨膜结构域，外显子5编码胞质尾。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HLA-DOB Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
