Marchf7 - membrane associated ring-CH-type finger 7

Predicted to enable MDM2/MDM4 family protein binding activity; ubiquitin binding activity; and ubiquitin conjugating enzyme binding activity. Predicted to be involved in several processes, including negative regulation of signal transduction by p53 class mediator; protein ubiquitination; and regulation of cellular protein metabolic process. Predicted to act upstream of or within negative regulation of T cell proliferation and regulation of tolerance induction. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Orthologous to human MARCHF7 (membrane associated ring-CH-type finger 7). [provided by Alliance of Genome Resources, Apr 2022]