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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Plekhg5 - pleckstrin homology and RhoGEF domain containing G5
Alias:
Tech
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够使鸟苷酸交换因子活性增强。预测涉及几个过程,包括内皮细胞趋化作用;I-kappaB激酶/NF-kappaB信号传导的正调控;以及在前突触调节蛋白质分解过程,调节突触传递。预测位于细胞间连接;细胞质;和膜瓣。预测在轴突;内体;和质膜中活性。这个基因的人类同源物与Charcot-Marie-Tooth疾病隐性中间C型和远端脊髓肌萎缩症4型有关。与人类的PLEKHG5(包含Pleckstrin同源性和RhoGEF结构域的G5)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:310999
ENSEMBL:ENSRNOG00000022694
UNIPROT:Q6RFZ7
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
310999
9
22
43520 bp
115.78
5
2
Plekhg5 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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