大鼠

Cdc14a - cell division cycle 14A

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种双特异性磷酸酶,优先去磷酸化细胞周期依赖的激酶底物以调节细胞周期。在人细胞系中,这种蛋白质定位在中期染色体上,并且转录本的耗竭导致中心体分离和胞质分裂缺陷。在鼠中,该蛋白质定位在I期被捕获卵母细胞的核内,然后成为减数分裂合格的卵母细胞中的分散物质。该蛋白质的敲除延迟了从I中期退出并导致具有染色体异常和高比例非整倍体的卵子,证明了在减数分裂调节中的功能。可变剪接导致多个转录变异体。[由RefSeq,2015年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
15
155388 bp
Unknown
12
2

Cdc14a Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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